par 1 inhibitor Search Results


par1 inhibitors vorapaxar (sch530348)  (Axon Medchem LLC)
90
Axon Medchem LLC par1 inhibitors vorapaxar (sch530348)
Par1 Inhibitors Vorapaxar (Sch530348), supplied by Axon Medchem LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
par1 inhibitors vorapaxar (sch530348) - by Bioz Stars, 2026-03
90/100 stars
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par1 antagonists  (Eisai Inc)
90
Eisai Inc par1 antagonists
Par1 Antagonists, supplied by Eisai Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/par1 antagonists/product/Eisai Inc
Average 90 stars, based on 1 article reviews
par1 antagonists - by Bioz Stars, 2026-03
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mark/par1 inhibitor  (Merck & Co)
90
Merck & Co mark/par1 inhibitor
Primary neurons at 15 DIV were pre-treated (30 min) with various kinases inhibitors including, Compound C (Comp C, 10 μM), <t>MARK/Par1</t> (20 μM), roscovitine (Rosco, 10 μM), PD98059 (PD98, 10 μM), H-89 (20 μM), Rapamycin (Rapa, 10 nM) and LY294002 (LY29, 20 μM) prior to AICAR treatment (1 mM, 2 h). Cell lysates were analyzed by WB for ACC, p-Ser 79 ACC (pACC), phosphorylated tau at epitopes Ser 262/356 and Thr 231 , total tau and actin ( a ). Quantification of phosphorylated tau at epitopes Ser 262/356 ( b ), and Thr 231 ( c ) expressed in ratio of Ctrl. Results represent mean ± SD, n = 4. a.u, arbitrary units. ***p < 0.001 compared to AICAR, One way ANOVA with Bonferroni’s post hoc test.
Mark/Par1 Inhibitor, supplied by Merck & Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mark/par1 inhibitor/product/Merck & Co
Average 90 stars, based on 1 article reviews
mark/par1 inhibitor - by Bioz Stars, 2026-03
90/100 stars
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vorapaxar (zontivity  (Merck & Co)
90
Merck & Co vorapaxar (zontivity
Primary neurons at 15 DIV were pre-treated (30 min) with various kinases inhibitors including, Compound C (Comp C, 10 μM), <t>MARK/Par1</t> (20 μM), roscovitine (Rosco, 10 μM), PD98059 (PD98, 10 μM), H-89 (20 μM), Rapamycin (Rapa, 10 nM) and LY294002 (LY29, 20 μM) prior to AICAR treatment (1 mM, 2 h). Cell lysates were analyzed by WB for ACC, p-Ser 79 ACC (pACC), phosphorylated tau at epitopes Ser 262/356 and Thr 231 , total tau and actin ( a ). Quantification of phosphorylated tau at epitopes Ser 262/356 ( b ), and Thr 231 ( c ) expressed in ratio of Ctrl. Results represent mean ± SD, n = 4. a.u, arbitrary units. ***p < 0.001 compared to AICAR, One way ANOVA with Bonferroni’s post hoc test.
Vorapaxar (Zontivity, supplied by Merck & Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/vorapaxar (zontivity/product/Merck & Co
Average 90 stars, based on 1 article reviews
vorapaxar (zontivity - by Bioz Stars, 2026-03
90/100 stars
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inhibitor of par-1 receptor r-99224/cs 747  (Sankyo Co)
90
Sankyo Co inhibitor of par-1 receptor r-99224/cs 747
Primary neurons at 15 DIV were pre-treated (30 min) with various kinases inhibitors including, Compound C (Comp C, 10 μM), <t>MARK/Par1</t> (20 μM), roscovitine (Rosco, 10 μM), PD98059 (PD98, 10 μM), H-89 (20 μM), Rapamycin (Rapa, 10 nM) and LY294002 (LY29, 20 μM) prior to AICAR treatment (1 mM, 2 h). Cell lysates were analyzed by WB for ACC, p-Ser 79 ACC (pACC), phosphorylated tau at epitopes Ser 262/356 and Thr 231 , total tau and actin ( a ). Quantification of phosphorylated tau at epitopes Ser 262/356 ( b ), and Thr 231 ( c ) expressed in ratio of Ctrl. Results represent mean ± SD, n = 4. a.u, arbitrary units. ***p < 0.001 compared to AICAR, One way ANOVA with Bonferroni’s post hoc test.
Inhibitor Of Par 1 Receptor R 99224/Cs 747, supplied by Sankyo Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/inhibitor of par-1 receptor r-99224/cs 747/product/Sankyo Co
Average 90 stars, based on 1 article reviews
inhibitor of par-1 receptor r-99224/cs 747 - by Bioz Stars, 2026-03
90/100 stars
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Image Search Results


Primary neurons at 15 DIV were pre-treated (30 min) with various kinases inhibitors including, Compound C (Comp C, 10 μM), MARK/Par1 (20 μM), roscovitine (Rosco, 10 μM), PD98059 (PD98, 10 μM), H-89 (20 μM), Rapamycin (Rapa, 10 nM) and LY294002 (LY29, 20 μM) prior to AICAR treatment (1 mM, 2 h). Cell lysates were analyzed by WB for ACC, p-Ser 79 ACC (pACC), phosphorylated tau at epitopes Ser 262/356 and Thr 231 , total tau and actin ( a ). Quantification of phosphorylated tau at epitopes Ser 262/356 ( b ), and Thr 231 ( c ) expressed in ratio of Ctrl. Results represent mean ± SD, n = 4. a.u, arbitrary units. ***p < 0.001 compared to AICAR, One way ANOVA with Bonferroni’s post hoc test.

Journal: Scientific Reports

Article Title: AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo

doi: 10.1038/srep26758

Figure Lengend Snippet: Primary neurons at 15 DIV were pre-treated (30 min) with various kinases inhibitors including, Compound C (Comp C, 10 μM), MARK/Par1 (20 μM), roscovitine (Rosco, 10 μM), PD98059 (PD98, 10 μM), H-89 (20 μM), Rapamycin (Rapa, 10 nM) and LY294002 (LY29, 20 μM) prior to AICAR treatment (1 mM, 2 h). Cell lysates were analyzed by WB for ACC, p-Ser 79 ACC (pACC), phosphorylated tau at epitopes Ser 262/356 and Thr 231 , total tau and actin ( a ). Quantification of phosphorylated tau at epitopes Ser 262/356 ( b ), and Thr 231 ( c ) expressed in ratio of Ctrl. Results represent mean ± SD, n = 4. a.u, arbitrary units. ***p < 0.001 compared to AICAR, One way ANOVA with Bonferroni’s post hoc test.

Article Snippet: AICAR, metformin, PD98059, H-89, LY294002 were purchased from Tocris; roscovitin and MARK/Par1 inhibitor from Merck; Compound C was from Santa-Cruz Biotechnology and rapamycin was from Cell Signaling Technology.

Techniques: